Peptide Database

Peptide NamePutative colicin activity protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC754H1174N194O205S7

DescriptionStandard

        MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSMPPGWGDYSPQGIALVQSVLFLELFAGLFLIKNLKRETGRDGLSVCIAPGETRKFPLHEQFLKMVYVVVCQNRLARLLFLLPVWSLLPEMSKKLFVLWLHSNWSR
    

Molecular Weight16461.02 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)0.67

Net Charge (pH 7.4) 0.29

Charge Density (pH 7.0) 0.0045

GRAVY Index0.09

Hydrophobic Moment 0.72

Boman Index0.16

Instability Index44.07

Aliphatic Index 96.71

Aromaticity 0.1007

Extinction Coeff. Reduced 31970.00

Extinction Coeff. Oxidized 32095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6270.84

LogP -49.11

H-bond Donors 217.0

H-bond Acceptors 215.0

Rotatable Bonds 528.0

Heavy Atoms 1160.0

Ring Count 34.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005589 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)