Peptide Database

Peptide NameCathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC849H1362N240O261S6

DescriptionStandard

        METQRDGSFLGWWSLVLLLLGLVTPLATAQALSYKEAVLRAVDGFNQRSSEANLYRLLDLEQQSKGDDDPDTPKPVNFLVKETVCSRTTQQPPEQCDFKEDGLVKRCVGTVTLDQIRGSFDITCDELQNTKKAARLGGFLRRGVEEFGRKLENIGRKIKEFFQNLAPRMES
    

Molecular Weight19299.74 Da

Isoelectric Point (pI)5.66

Net Charge (pH 7.0)-1.50

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0088

GRAVY Index-0.47

Hydrophobic Moment 0.90

Boman Index-0.10

Instability Index34.78

Aliphatic Index 83.22

Aromaticity 0.0760

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8181.38

LogP -88.32

H-bond Donors 285.0

H-bond Acceptors 266.0

Rotatable Bonds 657.0

Heavy Atoms 1356.0

Ring Count 22.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280070 VERIFIED: NO

Provenance & Taxonomy

OrganismOtolemur garnettii [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence