Peptide Database

Peptide NameAntimicrobial peptide VGF [554-578]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC132H202N46O32

DescriptionStandard

        TLQPPSALRRRHYHHALPPSRHYPG
    

Molecular Weight2945.31 Da

Isoelectric Point (pI)11.55

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.35

Charge Density (pH 7.0) 0.1498

GRAVY Index-1.30

Hydrophobic Moment 0.42

Boman Index-0.28

Instability Index190.53

Aliphatic Index 54.80

Aromaticity 0.0800

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1224.33

LogP -12.18

H-bond Donors 43.0

H-bond Acceptors 40.0

Rotatable Bonds 84.0

Heavy Atoms 210.0

Ring Count 11.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210639 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetMicrococcus luteus

MethodalamarBlue assay