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MYP_152777
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Basic Information
PMAP-23 [L5R,T19I]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C142H234N46O27
Standard
Sequence
RIIDRLWRVRRPQKPKFVIVWVR
Physicochemical Analysis
3017.67 Da
12.00
6.76
6.55
0.2939
-0.43
0.81
-0.32
47.57
118.26
0.1304
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1221.35
-4.85
46.0
34.0
98.0
215.0
7.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184642 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
1000 μg/mL
Hemolysis
PMID32666297 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32666297/
RECORD: Rec_0206476 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
0.0125 μg/mL
MIC
PMID32666297 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32666297/
RECORD: Rec_0247675 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. enterica serovar Choleraesuis C78-1 or serovar Typhimurium SL1344
0.39-0.78 μg/mL
MIC
PaperAnalogs of the Cathelicidin-Derived Antimicrobial Peptide PMAP-23 Exhibit Improved Stability and Antibacterial Activity.
RECORD: Rec_0249725 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. flexneri CICC 21534
75 μg/mL
MIC
PaperAnalogs of the Cathelicidin-Derived Antimicrobial Peptide PMAP-23 Exhibit Improved Stability and Antibacterial Activity.
RECORD: Rec_0249739 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Listeria monocytogenes CICC 21533
62.5 μg/mL
MIC
PMID32666297 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32666297/
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