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MYP_152733
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Basic Information
Callyaerin D
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
IIFPXPLXPINAI
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000612 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X(5)= 4-Hydroxyproline; X(8)=Daa
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0090560 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X(5)= 4-Hydroxyproline; X(8)=Daa
Bio-Activity Profile
Antimicrobial Anticancer
L5178Y
3.03 μM
ED50
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0135373 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X(5)= 4-Hydroxyproline; X(8)=Daa
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 20599387 PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0158453 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,8
Bio-Activity Profile
Antimicrobial Antibacterial
Mouse lymphoma L5178Y
3.03 μM
ED50
PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
RECORD: Rec_0391613 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,8
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
PMID20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20599387/
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