Peptide Database

Peptide NameDemidefensin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC352H576N108O106S6

DescriptionStandard

        MRTLALHTAMLLLVALHAQAEARQARADEAAAQQQPGADDQGMAHSFTWPENAALPLSESERGLRCICVLGICRLL
    

Molecular Weight8209.39 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-2.25

Net Charge (pH 7.4) -2.67

Charge Density (pH 7.0) -0.0296

GRAVY Index0.07

Hydrophobic Moment 0.66

Boman Index0.06

Instability Index24.93

Aliphatic Index 99.21

Aromaticity 0.0263

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3414.09

LogP -35.11

H-bond Donors 120.0

H-bond Acceptors 113.0

Rotatable Bonds 271.0

Heavy Atoms 572.0

Ring Count 9.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0183875 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9544

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic