Peptide Database

Peptide NameKininogen-2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC466H741N159O129

DescriptionStandard

        DERNNRDYTIRTRLHGHHKPSRNNRYAIKTSIHGHHIPRNVPESEEKTEQFLRDLPKINRKGPRPPGFSPFRGKFHSQSLRQIPGLGPLRG
    

Molecular Weight10634.86 Da

Isoelectric Point (pI)11.34

Net Charge (pH 7.0)11.38

Net Charge (pH 7.4) 10.80

Charge Density (pH 7.0) 0.1251

GRAVY Index-1.39

Hydrophobic Moment 0.85

Boman Index-0.36

Instability Index60.77

Aliphatic Index 55.71

Aromaticity 0.0659

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4684.97

LogP -53.53

H-bond Donors 163.0

H-bond Acceptors 147.0

Rotatable Bonds 350.0

Heavy Atoms 754.0

Ring Count 23.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205294 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyKininogen

Tax ID161274

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods90:Arginine amide

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour