Peptide Database

Peptide NameInterleukin-17A

Function Ontology

Antimicrobial ▸ Antifungal

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC655H1029N203O195S8

DescriptionStandard

        GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
    

Molecular Weight15123.94 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)3.33

Net Charge (pH 7.4) 2.66

Charge Density (pH 7.0) 0.0252

GRAVY Index-0.69

Hydrophobic Moment 0.55

Boman Index-0.13

Instability Index55.23

Aliphatic Index 73.71

Aromaticity 0.0606

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6406.29

LogP -72.80

H-bond Donors 222.0

H-bond Acceptors 213.0

Rotatable Bonds 480.0

Heavy Atoms 1061.0

Ring Count 30.0

Amide Bonds 149.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330798 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-17 family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide71-121; 76-123

Bio-Activity Profile

Function

Cytokine Growth factor IL-17 family Antifungal Host defense