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MYP_152520
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Basic Information
D-R7
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
7 amino acids
C42H86N28O8
Standard
Sequence
RRRRRRR
Physicochemical Analysis
1111.32 Da
12.00
6.76
6.56
0.9657
-4.50
0.08
-2.53
499.54
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
671.22
-8.85
29.0
15.0
41.0
78.0
0.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0182744 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
400 μM
MIC
PMID34021253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34021253/
RECORD: Rec_0184090 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oligoarginine/Polycationic
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with aminohexanoic space; lowercase source residues at positions 1,2,3,4,5,6,7 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
Jurkat
Fluorescence-based uptake assay
PMID11087855 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087855/
RECORD: Rec_0186669 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Labelled with fluorescein with aminohexanoic space
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0203379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
400 μM
MIC
PMID34021253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34021253/
RECORD: Rec_0237443 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibitor
Human cytomegalovirus (Furin); CHO
0.068 μM
Ki
PaperPolyarginines are potent furin inhibitors. | Cameron A, Appel J, Houghten RA, Lindberg I. | J Biol Chem. 2000 | PMID:10958789 PMID10958789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10958789/
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