Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC635H982N168O182S11

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKAGWFVERCWKNDIGYCRKRCLLLERYKLLCMNKQSCCIPLRSYDPYTQWPIHPNFFKNLDGEYVTRDDFPFSPDPGFTDEVTVKASVTQESRVTGATASQRDSS
    

Molecular Weight14234.32 Da

Isoelectric Point (pI)8.17

Net Charge (pH 7.0)1.53

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0124

GRAVY Index-0.26

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index41.23

Aliphatic Index 73.66

Aromaticity 0.1220

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5643.38

LogP -51.25

H-bond Donors 204.0

H-bond Acceptors 196.0

Rotatable Bonds 461.0

Heavy Atoms 996.0

Ring Count 26.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0388366 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence