Peptide Database

Peptide NameLECB_PHYAM

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length361 amino acids

Chemical FormulaC1614H2460N490O528S61

DescriptionStandard

        CDYNRCGRNFGFRTCPNELCCSSGGWCGSNDAHCGKGCQSQCDYWRCGVDFSGRVCPQGRCCSAWGWCGDTEEYCEEGCQSQCKLSSLPSPLSQILAIRKGKVCPDDLCCSVFGHCGVSVQHCGDGCQSQCVTNWRCGKDFDDRTCPKKLLCCSKDGWCGNTDAHCGEGCQSQCEQYNWRCGVDFGNRTCPNDLCCSVGGLNATIPTMAVEMKRISNSIVGMLVVVLSVMLLLPVEGHEGHGVVELIMGKLGAPECGREASWCGTTDDHCGEGCQSQCEQYNWHCGVDFGNRTCPNDLCCSEWGWCGITEGYCGEGCQSQCNHQRCGKDFAGRTCLNDLCCSEWGWCGSSEAHCGQGCQSN
    

Molecular Weight39131.73 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-13.86

Net Charge (pH 7.4) -15.46

Charge Density (pH 7.0) -0.0384

GRAVY Index-0.36

Hydrophobic Moment 0.63

Boman Index-0.02

Instability Index28.54

Aliphatic Index 47.20

Aromaticity 0.0748

Extinction Coeff. Reduced 80440.00

Extinction Coeff. Oxidized 83940.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028853 VERIFIED: YES

Provenance & Taxonomy

OrganismPhytolacca americana [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralityall-D amino-acid peptide [D]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme