Peptide Database

Peptide NameIYF

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC24H31N3O5

DescriptionStandard

IYF

Molecular Weight441.52 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0803

GRAVY Index2.00

Hydrophobic Moment 0.09

Boman Index0.94

Instability Index6.67

Aliphatic Index 130.00

Aromaticity 0.6667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 141.75

LogP 1.60

H-bond Donors 5.0

H-bond Acceptors 5.0

Rotatable Bonds 11.0

Heavy Atoms 32.0

Ring Count 2.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222049 VERIFIED: YES

Provenance & Taxonomy

OrganismHippophae rhamnoides [Plant]

Familyseabuckthorn seed meal protein-derived peptide

Tax ID193516

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory Antidiabetic

TargetDPP-IV

Activity5.32 ± 0.15 mM

MethodIC50