Peptide Database

Peptide NameB8

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC134H216N36O42S6

DescriptionStandard

        GIPCGESCAFLPCLTSLLGCTCQNKVCYRD
    

Molecular Weight3195.75 Da

Isoelectric Point (pI)6.15

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0098

GRAVY Index0.41

Hydrophobic Moment 0.31

Boman Index0.15

Instability Index36.24

Aliphatic Index 78.00

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1239.49

LogP -14.34

H-bond Donors 48.0

H-bond Acceptors 48.0

Rotatable Bonds 100.0

Heavy Atoms 218.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395104 VERIFIED: YES

Provenance & Taxonomy

OrganismHedyotis biflora [Animal]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetCapan-2

Activity2.14 μM

MethodIC50

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