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MYP_152459
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Basic Information
Phylloseptin-PBa1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C97H155N23O24
Standard
Sequence
FLSLIPHIASGIASLVKNF
Physicochemical Analysis
2027.41 Da
8.76
0.85
0.59
0.0445
1.23
0.53
0.49
17.19
148.95
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
736.81
-4.33
25.0
26.0
64.0
144.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0028211 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
5 μM
MIC
PaperPhylloseptin-PBa1, -PBa2, -PBa3: Three Novel Antimicrobial Peptides From the Skin Secretion of Burmeister's Leaf Frog (Phyllomedusa Burmeisteri)
RECORD: Rec_0057795 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0082789 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
200 μM
MIC
RECORD: Rec_0084770 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCPF 1467
20 μM
MIC
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0088913 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
Candida albicans
20 μM
MIC
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