Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC383H590N106O117S12

DescriptionStandard

        MKAFGVACAVDLACMFILESTAVPFSEVWRKNEEVGSIDSPVGEHQQPGGESMRPPVRSIESTSAGWCCSCCHNKGCGFCCKF
    

Molecular Weight8936.20 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-2.40

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0289

GRAVY Index0.01

Hydrophobic Moment 0.68

Boman Index0.09

Instability Index84.71

Aliphatic Index 55.18

Aromaticity 0.0843

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3514.88

LogP -39.82

H-bond Donors 129.0

H-bond Acceptors 129.0

Rotatable Bonds 287.0

Heavy Atoms 618.0

Ring Count 16.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0184472 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyHepcidin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial

MethodQualitative functional evidence