Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC683H1093N187O193S5

DescriptionStandard

        PTALLAAQEPMVLLAITEFVANSAAFVYFTAGALRRNISADTLPRRFPLQLKTKSMGQFSPKLQELYPDRPMELHLSARQQPLLSCHPDALHGALFGSAEAFVMLPNATRVPAFLLNIDANVTGKPTITGNRLGGTVSLTG
    

Molecular Weight15172.45 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)3.22

Net Charge (pH 7.4) 2.98

Charge Density (pH 7.0) 0.0229

GRAVY Index0.13

Hydrophobic Moment 0.51

Boman Index0.13

Instability Index44.36

Aliphatic Index 96.31

Aromaticity 0.0709

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5989.57

LogP -58.46

H-bond Donors 205.0

H-bond Acceptors 204.0

Rotatable Bonds 486.0

Heavy Atoms 1068.0

Ring Count 25.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339493 VERIFIED: NO

Provenance & Taxonomy

OrganismCorythaeola cristata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria