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MYP_152341
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Basic Information
CADY-1c (SEQ ID No: 4)
Anticancer
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
20 amino acids
C121H198N38O22
Standard
Sequence
GLWRALWRALRSLWKLKRKV
Physicochemical Analysis
2537.11 Da
12.00
6.76
6.55
0.3379
-0.34
0.92
-0.21
80.19
122.00
0.1500
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1009.48
-3.23
40.0
29.0
85.0
181.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060922 VERIFIED: NO
Provenance & Taxonomy
Synthetic construct [Synthetic]
CADY
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide
HeLa; HS-68 cells
Cellular uptake assay
Evidence URLhttps://patents.google.com/patent/US7943581 PatentUS7943581
RECORD: Rec_0292579 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
CADY
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperCandidate literature: PMID18957965 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957965/
RECORD: Rec_0356032 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
CADY
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PaperSelf-assembled peptide (CADY-1) improved the clinical application of doxorubicin.; Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo. PMID22688249;23000699 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22688249/ PatentUS7943581B2
RECORD: Rec_0359154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Cysteamide group
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/