Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC442H731N107O126S2

DescriptionStandard

        MTKATDSKFYALLSLSLLAVTSLALVIGNGSLIAANLGVSTGTAFTIVNFLDTWSSVATVITIVGMFTGVGTISAGVAASILAILKKKGKAKAAAF
    

Molecular Weight9624.30 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)4.49

Net Charge (pH 7.4) 4.27

Charge Density (pH 7.0) 0.0468

GRAVY Index1.04

Hydrophobic Moment 0.48

Boman Index0.41

Instability Index5.72

Aliphatic Index 125.10

Aromaticity 0.0729

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3674.68

LogP -35.74

H-bond Donors 132.0

H-bond Acceptors 133.0

Rotatable Bonds 319.0

Heavy Atoms 677.0

Ring Count 8.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216257 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus xiamenensis [Bacterium]

FamilyBacteriocin

Tax ID1178537

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal