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MYP_152282
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Basic Information
Uperin 3.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
17 amino acids
C84H145N23O22
Standard
Sequence
GVLDAFRKIATVVKNVV
Physicochemical Analysis
1829.19 Da
9.99
1.76
1.55
0.1035
0.90
0.78
0.21
2.72
142.94
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
743.48
-5.31
26.0
24.0
61.0
129.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0059606 VERIFIED: YES
Provenance & Taxonomy
Floodplain toadlet [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperNovel uperin peptides from the dorsal glands of the australian floodplain toadlet Uperoleia inundata.
RECORD: Rec_0110593 VERIFIED: NO
Provenance & Taxonomy
Uperoleia inundata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0278017 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0290296 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ638
RECORD: Rec_0334569 VERIFIED: YES
Provenance & Taxonomy
Uperoleia inundata [Animal]
Uperin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Leuconostoc mesenteroides
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP01147
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