Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC408H662N118O131S15

DescriptionStandard

        MKNFIVSVAVAVMLTIVCLQESSAAPSTEVEETMDGGPVAVYEEISEGSRMMSYGSVQRQRRCRFCCSCCPNMTTCGVCCRFGKEQQHL
    

Molecular Weight9797.31 Da

Isoelectric Point (pI)5.74

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0167

GRAVY Index0.04

Hydrophobic Moment 0.56

Boman Index0.02

Instability Index61.91

Aliphatic Index 64.49

Aromaticity 0.0562

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4010.88

LogP -48.08

H-bond Donors 149.0

H-bond Acceptors 146.0

Rotatable Bonds 326.0

Heavy Atoms 672.0

Ring Count 9.0

Amide Bonds 95.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0189267 VERIFIED: NO

Provenance & Taxonomy

OrganismNothobranchius furzeri [Animal]

FamilyHepcidin

Tax ID105023

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal