Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ FGF2-axis antiangiogenic context

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC72H121N23O23S

DescriptionStandard

        ESLARPCAPGAPAEARL
    

Molecular Weight1708.94 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-0.17

Net Charge (pH 7.4) -0.36

Charge Density (pH 7.0) -0.0100

GRAVY Index-0.17

Hydrophobic Moment 0.45

Boman Index-0.02

Instability Index56.63

Aliphatic Index 75.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 721.18

LogP -8.32

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 50.0

Heavy Atoms 119.0

Ring Count 3.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011131 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 58.8%, C 41.2% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Anti-angiogenic

RECORD: Rec_0026044 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPTX3 / Pentraxin 3

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

PTX3 FGF2-axis antiangiogenic context

TargetFGF2-stimulated endothelial cells

MethodEndothelial proliferation assay

RECORD: Rec_0030760 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPTX3 / Pentraxin 3

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

PTX3 FGF2-axis antiangiogenic context

TargetFGF2-stimulated endothelial cells

MethodCAM assay

RECORD: Rec_0038967 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0363368 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPTX3 / Pentraxin 3

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

PTX3 FGF2-axis antiangiogenic context

TargetFGF2-stimulated endothelial cells

MethodMigration assay