‹ ›
MYP_152212
← PREVIOUS NEXT → BACK
Basic Information
Esculentin-2LF1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C173H290N50O47S2
Standard
Sequence
GIFSLIKTAAKFVGKNLLKQAGKAGLEHLACKANNQC
Physicochemical Analysis
3886.59 Da
9.79
4.82
4.53
0.1304
0.08
0.64
0.09
8.11
97.84
0.0541
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1588.93
-16.05
55.0
55.0
137.0
272.0
3.0
41.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0397111 VERIFIED: YES
Provenance & Taxonomy
Amolops lifanensis [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecium 091299
12.5 μM
MIC
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0411626 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Esculentin
110118
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
31-37
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
Klebsiella pneumoniae 08040724
50 μM
MIC
PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0412700 VERIFIED: YES
Provenance & Taxonomy
Amolops lifanensis [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
0 % hemolysis at 6.3 μM
Hemolysis
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0419939 VERIFIED: YES
Provenance & Taxonomy
Amolops lifanensis [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
6.3 μM
MIC
FIRST PREV 1 ... 4 5 6
Showing 4 records on this page · Page 6 of 6