Peptide Database

Peptide NameCrotamine

Function Ontology

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Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC162H250N46O39S6

DescriptionStandard

        HCFPKEKICLPPSSDFGKMDCRWRWKCCKK
    

Molecular Weight3658.39 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.46

Charge Density (pH 7.0) 0.1599

GRAVY Index-0.88

Hydrophobic Moment 0.45

Boman Index-0.27

Instability Index89.07

Aliphatic Index 26.00

Aromaticity 0.1333

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1373.39

LogP -9.90

H-bond Donors 53.0

H-bond Acceptors 51.0

Rotatable Bonds 119.0

Heavy Atoms 253.0

Ring Count 10.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387430 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus durissus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)