Peptide Database

Peptide NameL-amino-acid oxidase (LAO) (Oh-LAAO) (EC 1.4.3.2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length491 amino acids

Chemical FormulaC2526H3895N667O741S16

DescriptionStandard

        MNDFLLLLLVLFLGVPRSENHVINLEECFQEPEYENWLATASHGLTKTLNPKKIVIVGAGISGLTAAKLFREAGHEVVILEASDRVGGRIKTHREDGWYVDVGPMRVPQTHRIVREYIKKFNISLNPFRQTDENAWYLIKHVRQKMSANNPENFGYQLNPNERGKSASQLFDETLDKVTDDCTLQKEKYDSFSTKEYLIKEGKLSTGAVEMIGDFLNEEAGFHNSFLISVMDHFLFLNNSFDEITGGFDQLPERFFKDMDSIVHLNSTVEKIVHINNKVTVFYEGLSTNMRLVADYVLITATARATRLIKFVPPLSIPKTRALRSLIYASATKIILVCTDKFWEKDGIHGGRSITDLPSRVIYYPNHDFTNGIGVLLASYTWYSDSEFYTTLSDEKCVDVVMDDLVEIHNVSKDYLKSVCGKHVVQKWALDQYSMGAFSTYTPYQITHYSQMLAQNEGRIYFAGEYTAHPHGWIETSMKSAIREAINIHNA
    

Molecular Weight55976.01 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-8.91

Net Charge (pH 7.4) -10.26

Charge Density (pH 7.0) -0.0181

GRAVY Index-0.25

Hydrophobic Moment 0.87

Boman Index0.04

Instability Index28.54

Aliphatic Index 88.33

Aromaticity 0.1100

Extinction Coeff. Reduced 71280.00

Extinction Coeff. Oxidized 71530.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003869 VERIFIED: YES

Provenance & Taxonomy

OrganismOphiophagus hannah [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Oxidoreductase Antiplatelet Cytolytic Toxin Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria