MYP_152039
Basic Information
Protegrin-1
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antibacterial Anti-Mycobacterium
Antimicrobial Anti-biofilm Biofilm inhibition
Antimicrobial Antifungal
Antiparasitic Antiprotozoal Anti-Trypanosoma
Antiparasitic General antiparasitic Antiparasitic
Antiviral
Antiviral Antiviral mechanism Viral replication inhibition Replication inhibitor
Enzyme modulation Enzyme inhibition Protease inhibition
Immunology Inflammation modulation Anti-inflammatory
Immunology Innate immune defense Host defense peptide Host defense activity
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Standard
18 amino acids
C88H150N36O20S4
Standard
Sequence
RGGRLCYCRRRFCVCVGR
Physicochemical Analysis
2160.62 Da
10.66
5.72
5.46
0.3177
-0.25
0.39
-0.44
62.13
53.89
0.1111
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
949.65
-10.62
42.0
30.0
71.0
148.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0425780 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Protegrin
9823;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibitor Replication inhibitor
Dengue 2 virus (Replication); MK2
11.7 μM
RT-PCR
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