‹ ›
MYP_152039
← PREVIOUS NEXT → BACK
Basic Information
Protegrin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C88H150N36O20S4
Standard
Sequence
RGGRLCYCRRRFCVCVGR
Physicochemical Analysis
2160.62 Da
10.66
5.72
5.46
0.3177
-0.25
0.39
-0.44
62.13
53.89
0.1111
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
949.65
-10.62
42.0
30.0
71.0
148.0
2.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0412965 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Protegrin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-15, 8-13
Bio-Activity Profile
Antimicrobial
PaperSynthesis and solution structure of the antimicrobial peptide protegrin-1 PMID8647100 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8647100/
RECORD: Rec_0414277 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ATCC 12834
4 μg/mL
MIC
PMID31214759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31214759/
RECORD: Rec_0416371 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 29212
2.7 μg/mL
MIC
PMID28382709;9257752;31214759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28382709/
RECORD: Rec_0416963 VERIFIED: YES
Provenance & Taxonomy
Porcine neutrophils [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 90028
2 μg/mL
PMID27331141 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27331141/
RECORD: Rec_0419045 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Natural peptide
9823
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
6-15, 8-13
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis RM24
MIC
PMID15245864 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15245864/
FIRST PREV 1 ... 22 23 24 25 NEXT LAST
Showing 5 records on this page · Page 24 of 25