‹ ›
MYP_152039
← PREVIOUS NEXT → BACK
Basic Information
Protegrin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C88H150N36O20S4
Standard
Sequence
RGGRLCYCRRRFCVCVGR
Physicochemical Analysis
2160.62 Da
10.66
5.72
5.46
0.3177
-0.25
0.39
-0.44
62.13
53.89
0.1111
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
949.65
-10.62
42.0
30.0
71.0
148.0
2.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0243500 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ATCC 12316
8 μg/mL
MBC
PMID31214759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31214759/
RECORD: Rec_0260454 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ATCC 25377
3.0 μg/mL
MIC
PMID31399625 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31399625/
RECORD: Rec_0261486 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Natural peptide
9823
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
6-15, 8-13
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis RM26
MIC
PMID15245864 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15245864/
RECORD: Rec_0268633 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anti-inflammatory
Staphylococcus aureus ATCC 33591 or MRSA
2 μg/mL
MIC
PaperSynthesis of protegrin-related peptides and their antibacterial and anti-human immunodeficiency virus activity
RECORD: Rec_0273887 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii ATCC 371484
2 μg/mL
MBC
PMID31214759 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31214759/
FIRST PREV 1 ... 12 13 14 15 16 ... 25 NEXT LAST
Showing 5 records on this page · Page 14 of 25