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MYP_151975
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Basic Information
SL175
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Standard
15 amino acids
C74H111N23O19
Standard
Sequence
GWAGWLLSPRGSRPS
Physicochemical Analysis
1626.82 Da
12.00
1.76
1.56
0.1173
-0.55
0.37
0.03
81.12
58.67
0.1333
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
669.21
-6.84
25.0
21.0
46.0
116.0
6.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0123537 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
50 %
Inhibition
PaperPubMed PMID: 19264632 PMID19264632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19264632/
RECORD: Rec_0171797 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Hepatitis C virus (Oligomerization); Huh7.5
50 %
ELISA
PaperPeptide inhibitors of hepatitis C virus core oligomerization and virus production. | Kota S, Coito C, Mousseau G, Lavergne JP, Strosberg AD. | J Gen Virol. 2009 | PMID:19264632 PMID19264632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19264632/
RECORD: Rec_0209249 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Infection inhibition
Hepatitis C virus(J6/JFH1) | Huh-7.5 cells
20 μM
% inhibition
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitors of hepatitis C virus core oligomerization and virus production. | Kota S, Coito C, Mousseau G, Lavergne JP, Strosberg AD. | J Gen Virol. 2009 Jun;90(Pt 6):1319-1328. | DOI:10.1099/vir.0.008565-0 | PMID:19264632 PMID19264632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19264632/
RECORD: Rec_0219912 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
hepatitis C virus(J6/JFH1):inhibition of viral infection in Huh-7
PaperPubMed PMID: 19264632 PMID19264632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19264632/
RECORD: Rec_0238133 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
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