‹ ›
MYP_151969
← PREVIOUS NEXT → BACK
Basic Information
Calcitonin gene-related peptide 1
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
37 amino acids
C162H263N49O53S2
Standard
Sequence
SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF
Physicochemical Analysis
3809.25 Da
7.82
0.53
0.24
0.0143
0.15
0.59
0.10
31.54
78.92
0.0541
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1646.34
-23.21
60.0
57.0
122.0
266.0
4.0
39.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0340949 VERIFIED: YES
Provenance & Taxonomy
Mus caroli [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0404706 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Calcitonin gene-related peptide
10090
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-7
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation ACE inhibitory Feeding regulator
Experimental: 9.00 (plasma half-life) minutes; /540 seconds; Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Calcitonin gene-related peptide 1 (Mus musculus): PMID 11761712##1911217 PMID11761712;1911217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11761712/
FIRST PREV 1 2
Showing 2 records on this page · Page 2 of 2