Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC156H229N41O41S2

DescriptionStandard

        FVNQHLCGSHLVEALYLVCGNDGFFYRPKA
    

Molecular Weight3398.87 Da

Isoelectric Point (pI)6.90

Net Charge (pH 7.0)-0.08

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0028

GRAVY Index0.21

Hydrophobic Moment 0.33

Boman Index0.20

Instability Index15.97

Aliphatic Index 87.67

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1308.27

LogP -9.79

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 106.0

Heavy Atoms 240.0

Ring Count 8.0

Amide Bonds 32.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0282192 VERIFIED: YES

Provenance & Taxonomy

OrganismHystrix cristata [Animal]

FamilyInsulin

Tax ID10137

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0330745 VERIFIED: YES

Provenance & Taxonomy

OrganismHystrix cristata [Animal]

FamilyInsulin

Tax ID10137

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0415523 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/