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MYP_151947
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Basic Information
Human Histatin 6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
25 amino acids
C139H207N55O34
Standard
Sequence
DSHAKRHHGYKRKFHEKHHSHRGYR
Physicochemical Analysis
3192.48 Da
10.62
6.37
5.80
0.2547
-2.54
0.40
-0.71
29.99
4.00
0.1200
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1469.68
-15.89
55.0
47.0
108.0
228.0
10.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0059447 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17174009 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17174009/
RECORD: Rec_0083090 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0139684 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
RECORD: Rec_0164562 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 2592, Micrococcus luteus
PaperStructural relation between human salivary histatins
RECORD: Rec_0381871 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Histatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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