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MYP_151930
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Basic Information
cTI
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C101H157N35O21S4
Standard
Sequence
KWCFRVCYRGICYRRCRG
Physicochemical Analysis
2325.81 Da
9.93
5.72
5.45
0.3176
-0.51
0.65
-0.39
8.33
37.78
0.2222
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
949.79
-7.37
42.0
31.0
74.0
161.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0298715 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0382931 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
6.7±0.6 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0387519 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
2.7±0.1 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0396202 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 6538
8 μM
MIC
PMID31455019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31455019/
RECORD: Rec_0420791 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli DC2 CGSC 7139
1 μM
MIC
PMID31455019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31455019/
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