MYP_151930
cTI
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
18 amino acids
C101H157N35O21S4
Standard
KWCFRVCYRGICYRRCRG
2325.81 Da
9.93
5.72
5.45
0.3176
-0.51
0.65
-0.39
8.33
37.78
0.2222
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
949.79
-7.37
42.0
31.0
74.0
161.0
5.0
17.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0158139
VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
HT-144
1.4±0.1 μM
CC50
RECORD: Rec_0177312
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus aureus ATCC 25923
2-8 μM
MIC
RECORD: Rec_0179586
VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
MCF-7
6.4±0.6 μM
CC50
RECORD: Rec_0261373
VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
Human RBCs
107±21 μM
CC50
RECORD: Rec_0284220
VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
MM96L
1.3±0.1 μM
CC50
Showing 5 records on this page · Page 2 of 3