Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC229H360N60O70S4

DescriptionStandard

        MKNTIKDFDLNLKSTKNEDASPSVGSRYLCTPGSCWKWVCFTTTVK
    

Molecular Weight5201.93 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)2.47

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0537

GRAVY Index-0.49

Hydrophobic Moment 0.46

Boman Index-0.07

Instability Index40.77

Aliphatic Index 55.00

Aromaticity 0.1087

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2126.07

LogP -23.72

H-bond Donors 78.0

H-bond Acceptors 77.0

Rotatable Bonds 170.0

Heavy Atoms 363.0

Ring Count 9.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204595 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus sanguinis SK408 [Bacterium]

FamilyLantibiotic

Tax ID888818

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal

RECORD: Rec_0402705 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus sanguinis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal