Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC430H697N141O121S7

DescriptionStandard

        VGSDLDAGRICGYGTARCRRNCKRQEFRVGKCPNTYPCCLKKWKVNSLNPQKDGKPKGAWLLEMAASQTSEPPFSAPSRRLHRAPRTRP
    

Molecular Weight10002.46 Da

Isoelectric Point (pI)10.21

Net Charge (pH 7.0)12.76

Net Charge (pH 7.4) 12.39

Charge Density (pH 7.0) 0.1434

GRAVY Index-0.94

Hydrophobic Moment 0.79

Boman Index-0.29

Instability Index49.79

Aliphatic Index 48.31

Aromaticity 0.0674

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4262.52

LogP -50.68

H-bond Donors 156.0

H-bond Acceptors 142.0

Rotatable Bonds 326.0

Heavy Atoms 699.0

Ring Count 18.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313497 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence