Peptide Database

Peptide NameEosinophil cationic protein (1-44)[C23,37S]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC240H370N76O61S

DescriptionStandard

        RPPQFTRAQWFAIQHISLNPPRSTIAMRAINNYRWRSKNQNTFL
    

Molecular Weight5328.04 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.85

Net Charge (pH 7.4) 6.59

Charge Density (pH 7.0) 0.1556

GRAVY Index-0.83

Hydrophobic Moment 0.47

Boman Index-0.19

Instability Index59.78

Aliphatic Index 62.27

Aromaticity 0.1364

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2266.56

LogP -23.26

H-bond Donors 79.0

H-bond Acceptors 70.0

Rotatable Bonds 168.0

Heavy Atoms 378.0

Ring Count 13.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0317271 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli BL2

Activity0.4 μM

MethodMIC

RECORD: Rec_0401110 VERIFIED: YES