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MYP_151820
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Basic Information
VA1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWXWKXVKXAK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0399240 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
VA1
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Didehydrophenylalanine (ΔF)
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antimalarial
Plasmodium falciparum 3D7
10 μM
IC50; Fluorimetry (SYBR Green I)
PMID22118799 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0400663 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida dubliniensis ATCC MAY-646
125 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0403905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida kefyr ATCC 2512
31.25 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0404894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida albicans F5
62.5 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0411394 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Neurospora crassa
72.32 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
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