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MYP_151820
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Basic Information
VA1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWXWKXVKXAK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006520 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical/modified peptide [Modified]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Hemolytic
human erythrocytes
30; 75 %
Hemolysis at 50 μM; Hemolysis at 100 μM
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0040617 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical or ambiguous residue annotation [Modified]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
bacterial, fungal and Plasmodium targets; human erythrocytes; HeLa cells
MIC; antiplasmodial IC50; hemolysis; cell-killing assays
PMID23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23876294/
RECORD: Rec_0046238 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical/modified peptide [Modified]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida albicans Gu4
62.5 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0056443 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical/modified peptide [Modified]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida tropicalis ATCC 750
15.62 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
RECORD: Rec_0081394 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical/modified peptide [Modified]
unspecified non-canonical residue at 3,6,9
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Candida parapsilosis ATCC 22019
125 μM
MIC
PMID22118799;23876294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22118799/
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