Peptide Database

Peptide NameSLAY-screened peptide P3107

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC112H167N35O27S

DescriptionStandard

        HPRTSPHRPCSFDWKYLARL
    

Molecular Weight2467.81 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)2.92

Net Charge (pH 7.4) 2.60

Charge Density (pH 7.0) 0.1462

GRAVY Index-1.09

Hydrophobic Moment 0.40

Boman Index-0.28

Instability Index38.29

Aliphatic Index 44.00

Aromaticity 0.1500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 992.94

LogP -8.22

H-bond Donors 37.0

H-bond Acceptors 33.0

Rotatable Bonds 72.0

Heavy Atoms 175.0

Ring Count 9.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371699 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/