‹ ›
MYP_151798
← PREVIOUS NEXT → BACK
Basic Information
Neuromacin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
59 amino acids
C284H437N89O85S8
Standard
Sequence
DCYEDWSRCTPGTSFLTGILWKDCHSRCKELGHRGGRCVDSPSKHCPGVLKNNKQCHCY
Physicochemical Analysis
6714.57 Da
8.49
3.03
2.49
0.0514
-0.82
0.71
-0.19
57.25
42.88
0.0847
13980.00
14480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2804.12
-33.30
107.0
100.0
217.0
466.0
14.0
61.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0074190 VERIFIED: YES
Provenance & Taxonomy
Medicinal leech [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus.MOA:bacteria: It aggregates bacteria
PaperMicrobial challenge promotes the regenerative process of the injured central nervous system of the medicinal leech by inducing the synthesis of antimicrobial peptides in neurons and microglia.
RECORD: Rec_0201869 VERIFIED: YES
Provenance & Taxonomy
Hirudo medicinalis [Animal]
Macin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus nishinomiyaensis
1.95-3.8 μM
MIC
PMID18606660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18606660/
RECORD: Rec_0256805 VERIFIED: YES
Provenance & Taxonomy
Hirudo medicinalis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 18606660 PMID18606660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18606660/
RECORD: Rec_0270521 VERIFIED: YES
Provenance & Taxonomy
Medicinal leech [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID18618271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18618271/
RECORD: Rec_0320470 VERIFIED: YES
Provenance & Taxonomy
Hirudo medicinalis [Animal]
Neuromacin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperJ Immunol. 2008 Jul 15;181(2):1083-95. | http://www.ncbi.nlm.nih.gov/pubmed/18606660 PMID18606660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18606660/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2