Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H160N30O34S4

DescriptionStandard

        GIVEQCCHKRCSIYDLENYCN
    

Molecular Weight2490.81 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.51

Charge Density (pH 7.0) -0.0566

GRAVY Index-0.45

Hydrophobic Moment 0.35

Boman Index-0.11

Instability Index60.62

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1063.78

LogP -11.29

H-bond Donors 40.0

H-bond Acceptors 38.0

Rotatable Bonds 82.0

Heavy Atoms 171.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234317 VERIFIED: YES

Provenance & Taxonomy

OrganismMyxine glutinosa [Animal]

FamilyInsulin

Tax ID7769

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour