Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC616H979N173O187S11

DescriptionStandard

        MSPLSTICRKKFEILYSERQNSSTIFEKANYGTKKPPKQSRISVVNKSTQQKTVTYARSKEHYTVFNWWDACIKLSSQCKNKCGEKEFQMAYCGRPTTLCCMKECDRVAIEEIHSQKEDKY
    

Molecular Weight14153.13 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)8.60

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.0711

GRAVY Index-0.85

Hydrophobic Moment 0.50

Boman Index-0.22

Instability Index68.59

Aliphatic Index 51.57

Aromaticity 0.0992

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5945.01

LogP -64.60

H-bond Donors 216.0

H-bond Acceptors 209.0

Rotatable Bonds 485.0

Heavy Atoms 987.0

Ring Count 20.0

Amide Bonds 132.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211891 VERIFIED: NO

Provenance & Taxonomy

OrganismVulpes vulpes [Bacterium]

FamilyDefensin

Tax ID9627

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence