Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length324 amino acids

Chemical FormulaC1634H2592N408O487S12

DescriptionStandard

        MDECSPKAESYELQNRAIVNIGISQIKKLLDIYLKMTICPALKTHLNDLNKQLWCYTLKATVSEYAEFDYSLMSVDISANSIEMGLKGVFNNTQQHIETPSPPPAFSLASQSTNMFYIAVSAFTINSAFMVLHQTNVSNIRITDEMVPSVSPIRLSTTTFGAFIPQISETHPDLKLDLKVKTEKEPIIKFEQDHVILQLLSTVTAYDVQSDDTPHKLFVLDLESVASVQITVEKGDLAFDLTLEKIEGNMNGKTLKFKKNNFLTVIMHDIVFPIIKAHLAKGFQLPGLLGSYIGKVHIVNPQVKVLEDYVLIGADIQFGENTSS
    

Molecular Weight36129.28 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-8.71

Net Charge (pH 7.4) -9.51

Charge Density (pH 7.0) -0.0269

GRAVY Index0.03

Hydrophobic Moment 0.63

Boman Index0.13

Instability Index41.38

Aliphatic Index 102.87

Aromaticity 0.0802

Extinction Coeff. Reduced 18910.00

Extinction Coeff. Oxidized 19035.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328822 VERIFIED: NO

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria