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MYP_151663
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Basic Information
Def-AcAA (hybrid defensins; Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
40 amino acids
C181H291N61O52S6
Standard
Sequence
ATCDLASIFNVNHALCAAHCIARRYRGGYCNSKAVCVCRN
Physicochemical Analysis
4346.01 Da
8.94
3.91
3.53
0.0977
0.20
0.52
0.00
20.69
78.25
0.0750
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1840.01
-22.97
72.0
64.0
139.0
300.0
5.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002203 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
dose causing the first signs of toxicity on mice
PaperPubMed PMID: 18214975 PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
RECORD: Rec_0009951 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 18214975 PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
RECORD: Rec_0140931 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
T1=100 mg/kg
PaperPubMed PMID: 18214975 PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
RECORD: Rec_0205288 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus strain 4
3.125 μg/mL
IC90
PaperPubMed PMID: 18214975 PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
RECORD: Rec_0225771 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
lethal dose
PaperPubMed PMID: 18214975 PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
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