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MYP_151658
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Basic Information
Jingdongin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
17 amino acids
C97H162N20O19S2
Standard
Sequence
FLPLFLPKIICVITKKC
Physicochemical Analysis
1976.58 Da
9.39
2.74
2.50
0.1610
1.42
0.58
0.41
22.64
154.71
0.1176
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
609.63
1.21
22.0
24.0
63.0
138.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006589 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial Antifungal
B. dysenteriae
35 μg/mL
MIC
PaperAntimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis
RECORD: Rec_0009082 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial Antifungal Toxicity
poor hemo.lytic
>200 μM
HC50
PaperAntimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis
RECORD: Rec_0015863 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 52.9%, C 47.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0062176 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
stapled cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
11-17
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
18.75 μg/mL
MIC
PMID22828809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22828809/
RECORD: Rec_0068588 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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