Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC940H1484N256O251S8

DescriptionStandard

        PVPLPVVHEPMLLLAVTEFVANSAAFTYFTAGALRRNISGDMLPRRFPLQLRTKSLGLFSPQLQERYPDQPMELQLWARQQPLLSCRPDALHGTLFSSVEAFVVLPNATRVPAFLLNIDANVTGKPSISGNRLRGTVRLMGGGSALPAPCPAQGLPVPQVTRLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight20643.92 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)5.20

Net Charge (pH 7.4) 4.91

Charge Density (pH 7.0) 0.0275

GRAVY Index0.13

Hydrophobic Moment 0.57

Boman Index0.14

Instability Index64.71

Aliphatic Index 97.51

Aromaticity 0.0794

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7907.95

LogP -91.32

H-bond Donors 270.0

H-bond Acceptors 267.0

Rotatable Bonds 641.0

Heavy Atoms 1455.0

Ring Count 44.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161011 VERIFIED: NO

Provenance & Taxonomy

OrganismCaloenas nicobarica [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria