Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC847H1304N228O269S12

DescriptionStandard

        MNDGTAEPARSPLESHPHPSDEHSGCSGIPLHFSEGHDSLLSYTFLFCSDICLQSSSGLSQPRCWKNNIGYCRSRCLDDERYIILCKNKLSCCIPIVFPSEFTRKPQPPLIRIEDITSDLGDWDTSPNSPVTKINDQFTFHDNLSLVFEKSTVDTSGTIQPMTTPMQLPFAAAD
    

Molecular Weight19369.56 Da

Isoelectric Point (pI)4.98

Net Charge (pH 7.0)-9.03

Net Charge (pH 7.4) -9.72

Charge Density (pH 7.0) -0.0519

GRAVY Index-0.38

Hydrophobic Moment 0.57

Boman Index0.00

Instability Index53.34

Aliphatic Index 70.06

Aromaticity 0.0805

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7879.34

LogP -89.66

H-bond Donors 275.0

H-bond Acceptors 278.0

Rotatable Bonds 617.0

Heavy Atoms 1356.0

Ring Count 38.0

Amide Bonds 186.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245099 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence