Peptide Database

Peptide NameDefensin-like protein 2 (Low-molecular-weight cysteine-rich protein 69) (Protein LCR69) (Plant defensin 2.2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Plant bioactivity ▸ Plant defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC360H582N114O100S13

DescriptionStandard

        MKLSMRLISAVLIMFMIFVATGMGPVTVEARTCESQSHRFKGTCVSASNCANVCHNEGFVGGNCRGFRRRCFCTRHC
    

Molecular Weight8524.02 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)6.69

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0869

GRAVY Index0.20

Hydrophobic Moment 0.64

Boman Index0.03

Instability Index40.13

Aliphatic Index 63.25

Aromaticity 0.0779

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3449.29

LogP -40.72

H-bond Donors 133.0

H-bond Acceptors 123.0

Rotatable Bonds 283.0

Heavy Atoms 587.0

Ring Count 10.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0065287 VERIFIED: YES

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]

FamilyDefensin

Tax ID3702

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Antifungal Non-hemolytic

RECORD: Rec_0101404 VERIFIED: NO

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]; Arabidopsis arenosa [Plant]

FamilyDefensin

Tax ID3702; 38785

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Plant defense Non-hemolytic Non-ribosomal

RECORD: Rec_0159641 VERIFIED: YES

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]

FamilyDefensin

Tax ID3702

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Protease inhibitor

RECORD: Rec_0425345 VERIFIED: NO

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]

FamilyDefensin

Tax ID3702

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Plant defense Non-hemolytic Non-ribosomal