Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length485 amino acids

Chemical FormulaC2429H3742N612O712S20

DescriptionStandard

        MCCFHQRGHSNMLLSVLLLFTSLSCTCGENPAIQFILSNKGLQYGKHVGTDWIQESLERVTFPDISGEVDIGLLGSIDYTLSDITIIKCDLPEPTVEFYPDATGFKTSVQGLSIALTGGWRTHYHIIDISGSFEMAIFNINVVSVVELGKDPNGHLSVSSVSCDADVGDVDIQFHGGASWIFQPFVRYFKRHITNEIQRNICPNVKGILVNLESYLQSMNVSFDVDQVLTLDLPLTGLPVINASGLNLGFKGEFYNIKTHMEPPFKAQPFTMSEQQGYMFSVGVSEFTLNSAAYAYYSAGLFQADINDSTVFQYVHVHLNTTTVGKFIPQLPHMFPDQLMSLKFYAREVPVFSFQPDAVKLGFQGAVKAFALQPNGTQSPLFTLSFDSKFSGKMYISGERLKGSIQMDNFTLTLAASEVGTFKTDALEKVLTIGIKFNVVTQVNKKLGEGFPLPRMKRAQLVNSVLNVEEGFIAMSSDAEVVLTD
    

Molecular Weight53550.67 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-13.47

Net Charge (pH 7.4) -14.50

Charge Density (pH 7.0) -0.0278

GRAVY Index0.09

Hydrophobic Moment 0.90

Boman Index0.16

Instability Index38.84

Aliphatic Index 91.38

Aromaticity 0.1093

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248901 VERIFIED: NO

Provenance & Taxonomy

OrganismChanna argus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria