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MYP_151467
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Basic Information
Polybia-MPII
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
14 amino acids
C76H128N18O18S
Standard
Sequence
INWLKLGKMVIDAL
Physicochemical Analysis
1614.00 Da
8.59
0.76
0.55
0.0542
0.87
0.56
0.35
15.79
167.14
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
589.84
-0.68
20.0
20.0
55.0
113.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0136702 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Rabbit erythrocytes
50 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/20195659/ PMID20195659 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20195659/
RECORD: Rec_0142765 VERIFIED: YES
Provenance & Taxonomy
Parachartergus vespiceps testaceus [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Chemotactic Cytotoxic Hemolytic
Staphylococcus aureus
PMID28108242;30974767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28108242/
RECORD: Rec_0151520 VERIFIED: YES
Provenance & Taxonomy
venom,the social wasp,Pseudopolybia vespiceps testacea [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperPubMed PMID: 28108242 PMID28108242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28108242/
RECORD: Rec_0163372 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Chemotactic Cytotoxic Hemolytic
Cryptococcus neoformans
PMID15150833;19463874;30974767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15150833/
RECORD: Rec_0171126 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 71.4%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
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